By Edited by Andrew D. Blann Edited by Gregory Y. H. Lip
ISBN-10: 0727917714
ISBN-13: 9780727917713
Urban clinic, Birmingham, united kingdom. Discusses the factors and results of blood clots, how antithrombotic treatment works and its makes use of for sufferers. Addresses bleeding hazards, venous thromboembolism, atrial traumatic inflammation, peripheral vascular disorder, middle failure, and anticoagulation. considerable halftone and colour illustrations. Softcover.
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Example text
In many patients the aetiology remains unknown. The major risk factors for ischaemic stroke include old age, male sex, obesity, hypertension, diabetes, and tobacco smoking. Symptomatic carotid stenosis >70% Major stroke Minor stroke Transient ischaemic attack Transient monocular blindness Asymptomatic carotid disease General elderly male population Antiplatelet treatment Aspirin is the only antiplatelet drug evaluated for the treatment of acute ischaemic stroke and is recommended early in the management at a dose of 160-325 mg daily.
Antiplatelet agents Among patients with vascular disorders (such as coronary artery disease, previous stroke or transient ischaemic attack, and peripheral vascular disease) antiplatelet agents substantially reduce the incidence of non-fatal stroke, non-fatal myocardial infarction, vascular mortality, and composite end point of stroke, myocardial infarction, and vascular death. A variety of antiplatelet drugs with varying mechanisms of action are used to minimise stroke in patients at high risk.
However, primary angioplasty is now proved to be an effective alternative and is used increasingly in preference to thrombolysis in many centres worldwide. Thrombolytic treatment Current key issues relate to the clinical situations in which thrombolysis may be beneficial or contraindicated. For example, all patients with a history suggesting cardiac ischaemia and accompanying electrocardiographic changes indicating acute myocardial infarction should be considered for thrombolysis. However, patients with only ST segment depression on an electrocardiogram or with a normal electrocardiogram do not benefit from thrombolysis, and treatment should therefore be withheld.
ABC of Antithrombotic by Edited by Andrew D. Blann Edited by Gregory Y. H. Lip
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