Download e-book for iPad: Chronic Myeloproliferative Disorders by Mughal T., Goldman J.M.

By Mughal T., Goldman J.M.

ISBN-10: 0415415985

ISBN-13: 9780415415989

With the recent class of power myeloproliferative issues, and the increase of curiosity in molecularly detailed remedies, Informa Healthcare with Dr. Mughal and Dr. Goldman speak about the cutting-edge developments and new and present implications within the prognosis, therapy, and administration of patients.Filled with cutting edge details in terms of stem-cell transplantations and entire colour images, this well-illustrated textual content can be a vital source for all practitioners in hematologic oncology.

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Pendergast AM. The Abl family kinases: mechanisms of regulation and signaling. Adv Cancer Res 2002; 85: 51–100. 48. Hantschel O, Superti-Furga G. Regulation of the c-Abl and Bcr-Abl tyrosine kinases. Nat Rev Mol Cell Biol 2004; 5: 33–44. 49. Barila D, Superti-Furga G. An intramolecular SH3-domain interaction regulates c-Abl activity. Nat Genet 1998; 18: 280–2. 50. Pluk H, Dorey K, Superti-Furga G. Autoinhibition of c-Abl. Cell 2002; 108: 247–59. 51. Smith KM, Yacobi R, van Etten RA. Autoinhibition of Bcr-Abl through its SH3 domain.

Translocation of c-abl oncogene correlates with the presence of a Philadelphia chromosome in chronic myelocytic leukaemia. Nature 1983; 306: 277–80. 8. Groffen J, Stephenson JR, Heisterkamp N et al. Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22. Cell 1984; 36: 93–9. 33 9. Abelson HT, Rabstein LS. Lymphosarcoma: virus induced thymic-independent disease in mice. Cancer Res 1970; 30: 2213–22. 10. Scher CD, Siegler R. Direct transformation of 3T3 cells by Abelson murine leukaemia virus.

Hochhaus A, Reiter A, Skladny H et al. A novel BCR-ABL fusion gene (e6a2) in a patient with Philadelphia chromosome negative chronic myelogenous leukemia. Blood 1996; 88: 2236–40. 41. Advani AS, Pendergast AM. Bcr-Abl variants: biological and clinical aspects. Leuk Res 2002; 26: 713–20. 42. Demehri S, Paschka P, Schultheis B et al. e8a2 BCRABL: more frequent than other atypical BCR-ABL variants? Leukemia 2005; 19: 681–4. 43. Barnes DJ, Melo JV. Cytogenetic and molecular genetic aspects of chronic myeloid leukaemia.

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Chronic Myeloproliferative Disorders by Mughal T., Goldman J.M.

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