By Joseph Brusha, Roberto Viacava
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The vascular porosity occupied by bone fluid is the space outside the blood vessels and nerves in the Volkmann and Haversian canals (Fig. 2, Fig. 3). This bone fluid freely exchanges with the vascular The Plumbing of Long Bones 47 Figure 1. Schematic diagram showing the vascular arrangement in the long bone diaphysis. A. Williams, R. H. Kelly, “Microcirculation of Bone,” in The physiology and pharmacology of the microcirculation, Vol. 2, Academic Press, (1984). 48 S. C. Cowin Outer circumferential IomeQae isels , 'S Figure 2.
This creates a major barrier for the project. To realise the LHDL it is necessary a long list of technological skills and a huge economical investment, that no single research group or single country can finance and realise. In the proposal we submitted to the European Commission we forecasted a total cost of nearly15 Millions Euro over five years (10 of EC support plus 5 of co-granting). The total value of the resources the project would mobilise in terms of data collections, usage of large-scale infrastructures, and value of the results from previous researches the partner planned to bring into the project, was predicted to be over 40 Millions Euro.
The influence of the mechanical loading of a whole bone on the fluid systems’ maintenance of the bone tissue is critical. The fluid flow resulting from the mechanical loading is modeled by the theory of poroelasticity. This theory models the interaction of deformation and fluid flow in a fluid-saturated porous medium. The theory was proposed by Biot [4,5] as a theoretical extension of soil consolidation models developed to calculate the settlement of structures placed on fluid-saturated porous soils.
Grimm Fairy Tales #53 Nov 2010 by Joseph Brusha, Roberto Viacava
by Thomas
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