By Jerome Groopman
ISBN-10: 0547053649
ISBN-13: 9780547053646
How medical professionals imagine is a window into the brain of the health care professional and an insightful exam of the all-important dating among medical professionals and their sufferers. during this myth-shattering paintings, Jerome Groopman explores the forces and concept procedures at the back of the selections medical professionals make. He pinpints why medical professionals be successful and why they err. most vital, Groopman exhibits whilst and the way medical professionals can -- with our support -- keep away from snap judgments, include uncertainty, speak successfully, and set up different abilities which may profoundly impression our future health.
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Sample text
The purpose of the study was to demonstrate that PCI was non-inferior to CABG in this patient subset. The trial was stopped early due to slow enrolment and as such, the event rates used for sample size calculations could not be achieved. Nevertheless, the incidence of the primary endpoint of death, non-fatal MI, and non-fatal stroke at one year was similar for both strategies although non-inferiority could not be proven. There was again a significant reduction in the incidence of repeat revascularization for those having had CABG.
All observations were normal as was a troponin T and repeat ECG that showed no acute ischaemia. The patient was discharged home later that evening. Learning point The evolution of dual antiplatelet therapy The central role of platelets in the propagation of intracoronary thrombi has made antiplatelet therapy central to the management of atherothrombotic cardiovascular disease. Over the last two decades, aspirin has become the cornerstone of antiplatelet therapy [1]. Its antithrombotic action is mediated through the irreversible acetylation of cyclooxygenase (COX) enzymes secreted by activated platelets.
The purpose of the study was to demonstrate that PCI was non-inferior to CABG in this patient subset. The trial was stopped early due to slow enrolment and as such, the event rates used for sample size calculations could not be achieved. Nevertheless, the incidence of the primary endpoint of death, non-fatal MI, and non-fatal stroke at one year was similar for both strategies although non-inferiority could not be proven. There was again a significant reduction in the incidence of repeat revascularization for those having had CABG.
How Doctors Think by Jerome Groopman
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