By Mark T Friedman, Kamille A West, Peyman Bizargity
ISBN-10: 3319223410
ISBN-13: 9783319223414
This quantity is a suite of immunohematology and transfusion medication circumstances, constructed from medical vignettes and antibody panels with questions in keeping with every one case, prepared in a workbook structure. The instances are in response to actual sufferer difficulties that are generally encountered and covers a couple of universal concerns and difficult difficulties in blood banking and transfusion perform. dialogue and backbone of every case is equipped in a separate resolution part, together with up to date details on pertinent advances within the field.
Written via specialists within the box, Immunohematology and Transfusion medication: A Case research process offers an interactive instrument to assist make blood banking and transfusion medication memorable, useful, and correct to citizens and fellows.
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Additional info for Immunohematology and Transfusion Medicine: A Case Study Approach
Sample text
6. What additional testing should be done to confirm the cause of the baby’s positive DAT? 7. Should the mother receive postpartum RhIg? Why or why not? Answers 1. What is the mother’s ABO/Rh type? The mother is group O negative. See Chap. #1, question 1 answer for explanation. 2. What possible antibodies are evident in the mother from the panel results? The panel shows apparent antibody specificity to D and C antigens. Given that the rG cell (cell #10: D−, C−, G+) is reactive with the mother’s serum, anti-G antibody is present.
Would antibody titration using the rG cell (panel cell #10) be of any help in your decision? Why or why not? Given that anti-G is present, the reported antibody titer may solely reflect that of the G antibody, and, in fact, anti-D may not even be present. Thus, since the mother is Rh negative, a standard prenatal 300 µg dose RhIg should be administered at 28 weeks of gestation. However, titration of the antibody using the rG cell could be helpful in that if the titer result is about the same as that for the R2 and r′ cells, then the titer most likely reflects anti-G alone (without anti-D), whereas a significantly lower titer with the rG cell may be suggestive of the presence of anti-D such that RhIg would not be indicated.
Bethesda: AABB; 2014. 328. Chapter 11 Hide and Seek Clinical History A 70-year-old male with myelodysplastic syndrome presents for outpatient transfusion. 7 g/dL. The patient received two units of red blood cells (RBCs) 2 months ago, and the antibody screen was negative at that time. A type and crossmatch sample (ethylenediaminetetraacetic acid, EDTA anticoagulant) is submitted to the blood bank; two units of RBCs are requested for the patient. ABO/Rh/Antibody Screen ABO/Rh (gel method) Patient RBCs (forward typing) Anti-A Anti-B Anti-D 0 4+ 0 Antibody screen (gel method) SC1 W+ SC2 0 Reaction scale = 0 (no reaction) to 4 + (strong reaction) RBC red blood cells, SC screen cell Patient plasma (reverse typing) A1 cells B cells 4+ 0 © Springer International Publishing Switzerland 2016 M.
Immunohematology and Transfusion Medicine: A Case Study Approach by Mark T Friedman, Kamille A West, Peyman Bizargity
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