Download PDF by M. Flint Beal, Dr Anthony E. Lang, Albert C. Ludolph: Neurodegenerative Diseases: Neurobiology, Pathogenesis and

By M. Flint Beal, Dr Anthony E. Lang, Albert C. Ludolph

ISBN-10: 052181166X

ISBN-13: 9780521811668

Neurodegenerative illnesses are significant participants to incapacity and affliction, with Alzheimer's and Parkinson's illnesses the main general. This significant reference studies the speedily advancing wisdom of pathogenesis and therapy of neurodegenerative ailments within the context of a entire survey of every illness and its scientific positive factors. The editors and members are one of the major specialists within the box the world over. protecting simple technological know-how, diagnostic instruments and healing ways, the ebook specializes in all features of neurodegenerative ailment, together with the traditional getting older method. The dementias, prion illnesses, Parkinson's ailment and unusual parkinsonisms, neurodegenerative ataxias, motor neuron ailments, degenerative illnesses with chorea, iron and copper issues, and mitochondrial ailments, are all methodically awarded and mentioned, with vast illustrations. In every one case the underlying genetics, neuropathological and medical matters are absolutely reviewed, making this the main whole in addition to the main authoritative reference to be had to clinicians and neuroscientists.

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Weisiger, R. A. & Fridovich, I. (1973). Mitochondrial superoxide simutase. Site of synthesis and intramitochondrial localization. J. Biol. , 248 (13), 4793–6. Weiss, S. , Test, S. , Eckmann, C. M. et al. (1986). Brominating oxidants generated by human eosinophils. Science, 234 (4773), 200–3. , Etienne, F. & Hoshi, T. (2002). Peptide methionine sulfoxide reductase: structure, mechanism of action, and biological function. Arch. Biochem. , 397 (2), 172–8. Winterbourn, C. C. (1995). Toxicity of iron and hydrogen peroxide: the Fenton reaction.

Lusis, A. J. & Reynolds, W. F. (2001a). Mice lacking myeloperoxidase are more susceptible to experimental autoimmune encephalomyelitis. J. , 112 (1–2), 97–105. Brennan, M. , Anderson, M. , Shih, D. M. et al. (2001b). Increased atherosclerosis in myeloperoxidase-deficient mice. J. Clin. , 107 (4), 419–30. Brigelius-Flohe, R. (1999). Tissue-specific functions of individual glutathione peroxidases. Free Radic. Biol. , 27 (9–10), 951– 65. Brodie, A. E. & Reed, D. J. (1987). Reversible oxidation of glyceraldehyde 3-phosphate dehydrogenase thiols in human lung carcinoma cells by hydrogen peroxide.

1999). Excitotoxicity and mitochondria. Biochem. Soc. , 66, 55– 67. Nishikimi, M. (1975). Oxidation of ascorbic acid with superoxide anion generated by the xanthine-xanthine oxidase system. Biochem. Biophys. , 63 (2), 463–8. Noh, K. M. & Koh, J. Y. (2000). Induction and activation by zinc of NADPH oxidase in cultured cortical neurons and astrocytes. J. , 20 (23), RC111. Nordberg, J. & Arner, E. S. (2001). Reactive oxygen species, antioxidants, and the mammalian thioredoxin system. Free Radic. Biol.

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Neurodegenerative Diseases: Neurobiology, Pathogenesis and Therapeutics by M. Flint Beal, Dr Anthony E. Lang, Albert C. Ludolph


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