By Dr. John French (auth.), Stewart Wolf (eds.)
ISBN-10: 1468481304
ISBN-13: 9781468481303
ISBN-10: 1468481320
ISBN-13: 9781468481327
The current quantity comprises the 1st 1/2 the edited tran script of a six-day convention, "Fundamental facts on Reactions of Vascular Tissue in Man," held April 19-25, 1970, in Lindau, West Germany. the rest of the lawsuits, facing the epide miologic, scientific and preventive facets of arteriosclerosis, can be released in a moment quantity. The convention was once held lower than the auspices of the overseas Society of Cardiology, the foreign Cardiology starting place and the eu Atherosclerosis team. the purpose of the convention used to be to accomplish a synthesis of current wisdom touching on arterioscle rosis. for that reason, staff have been introduced jointly from numerous coun attempts and from a variety of disciplines that don't more often than not intercom municate at no cost alternate of information and ideas. Six extensive topic components have been brought through unmarried papers; 3 of them are integrated during this quantity. within the dialogue which each one formal pres entation, the members tried to reconcile disparate information and interpretations and to arrive .a transparent identity of significant components of lack of information and of the most important questions for destiny examine. The layout of the court cases doesn't persist with accurately that of the convention itself. The formal papers are incorporated, a little bit ab breviated, and excerpts of the dialogue were amassed lower than a sequence of themes prepared in logical series. for that reason, the quoted statements don't inevitably seem so as or within the position within the application the place they have been made. central matters, syntheses and unanswered questions are interspersed one of the themes as edi torial comments.
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Additional info for The Artery and the Process of Arteriosclerosis: Pathogenesis The first half of the Proceedings of an Interdisciplinary Conference on Fundamental Data on Reactions of Vascular Tissue in Man April 19–25, 1970, Lindau, West Germany
Sample text
The results of these investigations on changes of connective tissue and calcium metabolism are demonstrated in FIG. 14. You can see that immediately after vitamin D administration the metabolism of connective tissue, in this case measured by incorporation of 35S-su1fate into sulfated mucopo1ysaccharides of arterial connective tissue, markedly increased. When this mesenchymal reaction begins to decrease, there is an increase of 45 calcium incorporation and, somewhat later, of total calcium content of the tissue.
Acid Toluidine Blue (for comparison with FIG. 18). ARTERIAL STRUCTURE AND FUNCTION 49 FIGURE 20. A. Electron micrograph of human coronary intimal layer showing early stages of calcification (C) in altered collagen fibers (c) surrounding myointimal cell (atherophil) (A) and an enlarged membrane bound lipid droplet (L). Uranyl Acetate - Lead Hydroxide Staining l3,10QX 50 CHAPTER 1 B. Enlargement of similar area as in A showing increased electron density of pseudoelastin or altered collagen fibers (c) surrounding amorphous dense deposits that seem to use these fibers as a matrix for deposition of Ca.
Gross and his associates have studied the coronary arteries of newborn infants and older children, and demonstrated a proliferation of intimal smooth muscles without rupture of the elastica. The new smooth muscle cells migrate into the developing intima through naturally occurring openings in the plate of the internal elastic lamina. In the intima they run longitudinally rather than circularly. This, according to these authors, provides means for the longit~dina1 stretch. We have repeated and confirmed these studies.
The Artery and the Process of Arteriosclerosis: Pathogenesis The first half of the Proceedings of an Interdisciplinary Conference on Fundamental Data on Reactions of Vascular Tissue in Man April 19–25, 1970, Lindau, West Germany by Dr. John French (auth.), Stewart Wolf (eds.)
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