By Eugene Toy, Gary C. Rosenfeld, David Loose, David S. Briscoe
REAL-LIFE medical instances FOR the elemental SCIENCES AND USMLE STEP 1
Experience with medical instances is vital to excelling at the USMLE Step 1 and shelf checks, and finally to supplying sufferers with useful scientific care. Case documents: Pharmacology offers fifty six true-to-life clinicalcases that illustrate crucial ideas in pharmacology. each one case contains an easy-to-understand dialogue correlated to key easy technology thoughts, definitions of key phrases, pharmacology pearls, and USMLE-style overview questions.
With Case records, you'll examine rather than memorize.
• research from fifty six high-yield instances, each one with board-style questions
• grasp key techniques with medical pearls
• Polish your method of medical difficulties and to sufferer care
• Maximize your board ratings with the confirmed Case documents system
Read Online or Download Case Files Pharmacology (3rd Edition) PDF
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Extra info for Case Files Pharmacology (3rd Edition)
Scopolamine blocks muscarinic cholinoreceptors in the vestibular system and CNS to prevent motion sickness. It has a relatively long duration of action and can be given as a transdermal patch, making it well suited for the treatment of motion sickness. Histamine H1-receptor antagonists, such as cyclizine, are also used to treat motion sickness. In addition to motion sickness, muscarinic cholinoreceptor antagonists (eg, benztropine) are used therapeutically to treat Parkinson disease. Short-acting topical agents or ointments are used to facilitate ophthalmoscopic examination (eg, cyclopentolate, tropicamide).
Sparr HJ, Beaufort TM, Fuchs-Buder T. Newer neuromuscular blocking agents. How do they compare with established drugs? Drugs. 2001;61(7):919–42. 39 CASE FILES: PHARMACOLOGY CASE 5 A 75-year-old woman with mild congestive heart failure is admitted to the intensive care unit (ICU) with sepsis caused by a urinary tract infection. She is hypotensive, with a blood pressure of 80/40 mm Hg, has an elevated heart rate (tachycardia) and decreased urine output (oliguria). Along with the institution of appropriate antibiotic therapy and IV fluids, a decision is made to start her on an IV infusion of norepinephrine to attempt to raise her blood pressure.
Vasopressive agents are used in patients where aggressive fluid resuscitation is contraindicated, such as those with congestive heart failure, kidney failure, liver failure, or acute respiratory distress syndrome (ARDS); these patients risk development of pulmonary edema. Although previously, dopamine was frequently used to treat this condition. The β1-adrenoceptor-mediated effects in the heart result in an increase in cardiac output with minimal peripheral vasoconstriction. This contributes to dopamine’s ability to raise systolic blood pressure with no effect or only a slight effect on diastolic pressure.
Case Files Pharmacology (3rd Edition) by Eugene Toy, Gary C. Rosenfeld, David Loose, David S. Briscoe