By Professor Audrey Chapman Ph.D.
ISBN-10: 1107653347
ISBN-13: 9781107653344
The way during which genetic examine linked to dependancy is carried out, interpreted and translated into scientific perform and coverage projects increases very important social, moral and criminal matters. Genetic study on dependancy fulfils key goals; the 1st is to spot the moral matters and specifications bobbing up whilst accomplishing genetically-based dependancy study, and the second one is to discover the moral, criminal and public coverage implications of studying, translating and utilizing this learn. The e-book describes learn instructions on human security matters similar to bettering the expert consent procedure, retaining privateness, tasks to minors and deciding on even if to just accept investment. the wider public healthiness coverage implications of the study are explored and guidance provided for constructing potent social interventions. hugely suitable for clinicians, researchers, teachers and policy-makers within the fields of dependancy, psychological wellbeing and fitness and public coverage.
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Additional info for Genetic Research on Addiction: Ethics, the Law, and Public Health
Sample text
Addiction, 103, 360–367. , Laforge, K. , et al. (1998). Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity: possible implications for opiate addiction. Proceedings of the National Academy of Sciences USA, 95, 9608–9613. Bosron, W. , Magnes, L. , and Li, T. K. (1983). Kinetic and electrophoretic properties of native and recombined isoenzymes of human liver alcohol dehydrogenase. Biochemistry, 22, 1852–1857. Buckland, P. R. (2001). Genetic association studies of alcoholism: problems with the candidate gene approach.
And Dana, F. W. (2004). An epidemiologic assessment of genomic profiling for measuring susceptibility to common diseases and targeting interventions. Genetics in Medicine, 6, 38–47. Kim, S. , Kim, C. , Kang, D. , et al. (2004). Association of functional opioid receptor genotypes with alcohol dependence in Koreans. Alcoholism, Clinical and Experimental Research, 28, 986–990. Lee, S. , Lee, J. , et al. (2010). MAOA interacts with the ALDH2 gene in anxiety-depression alcohol dependence. Alcoholism, Clinical and Experimental Research, 34, 1212–1218.
2003). , 2004a). , ADH4, ADH5, ADH6, and ADH7) increase the risk of AD because they result in lower levels of the aversive acetaldehyde. Twelve single nucleotide polymorphisms (SNP) associated with the ADH4 gene have been correlated with a greater risk for AD in European Americans (Edenberg and Foroud, 2006). , 2006). , 2009). These neurotransmitter signaling systems are central to neural circuits for a range of cognitions and behaviors involved in AD, such as reward and reinforcement, learning and memory, emotion and affect regulation, stress, impulse inhibition, and executive control (Koob and Le Moal, 2006).
Genetic Research on Addiction: Ethics, the Law, and Public Health by Professor Audrey Chapman Ph.D.
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