Animal Cell Technology: From Vaccines to Genetic Medicine - download pdf or read online

By C. Weissmann (auth.), Manuel J. T. Carrondo, Bryan Griffiths, José L. P. Moreira (eds.)

ISBN-10: 9401062730

ISBN-13: 9789401062732

ISBN-10: 940115404X

ISBN-13: 9789401154048

Animal phone know-how has gone through a fast transformation over the past decade from a learn instrument and hugely specialized know-how to a critical source for innovation in pharmaceutical examine and improvement. those complaints of the 14th assembly of the ecu Society for Animal telephone expertise (Vilamoura, Portugal, may perhaps 1996) elevate up to now the historic viewpoint of animal phone know-how for the advantage of society, `From Vaccines to Genetic Medicine', and may constitution this important expertise for the years yet to come.
robust contributions are grouped within the conventional ESACT parts of 'Cell and body structure Engineering' facing cellphone country, together with genetics, and its atmosphere, and 'Animal phone method Engineering' overlaying integration of bioreaction with bioseparation coupled with online tracking to enhance protein creation and consistency. broad assurance of metabolic engineering on synthesis, folding, meeting, transiting and secretion is handled within the consultation on 'Recombinant Proteins: Biosynthesis and Bioprocessing'. conventional yet increasing parts of animal telephone expertise relevance are highlighted within the wide periods of 'Animal Cells as instruments for Discovery and trying out' and 'Animal telephone Vaccines: current and Future'. classes eventually disguise the more moderen domain names of animal mobilephone expertise paintings - 'Tissue Engineering and Biomedical units' and 'Cells and Vectors for Genetic drugs' - the place you can actually foresee a really vivid future.

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265:10893-9. 17. Lodish, H. , and N. Kong. 1993. The secretory pathway is normal in dithiothreitol- treated cells, but disulfide bonded proteins are reduced and reversibly retained in the endoplasmic reticulum. J. Bioi. Chem. 268:20598-20605. 18. Lyles, M. , and H. F. Gilbert 1991. Catalysis of the oxidative folding of ribonuclease A by protein disulfide isomerase: dependence of the rate on the composition of the redox buffer. Biochemistry. 30:613-9. 19. Stamnes, M. , and C. S. Zuker. 1990. Peptidyl-prolyl cis-trans isomerases, cyclophilin, FK506-binding protein, and ninaA: four of a kind.

TOWARD A DNA VACCINE AGAINST LYSSAVIRUSES. C. Bahloul, F. Fouque, N. Tordo, Y. Jacob and P. Perrin. Laboratoire des Lyssavirus lnstitut Pasteur, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France Abstract Classical rabies vaccine strains (genotype 1) protect inefficiently against rabies-related lyssaviruses (other genotypes) and in particular against the Mokola virus (genotype 3). DNA vaccine modem approach was used to produce Mokola valency. Purified Plasmid vector was injected into each anterior tibialis muscle of BALB/c mice.

Folding and assembly of viral membrane proteins. Virology. 193:545-62. 6. Gething, M. , and J. Sambrook. 1992. Protein folding in the cell. Nature. 355:3345. 7. , and A. Helenius. 1995. Quality control in the secretory pathway. Curr Opin Cell Biol. 7:523-9. 8. Hilton, D. , S. S. Watowich, P. J. Murray, and H. F. Lodish. 1995. Increased cell surface expression and enhanced folding in the endoplasmic reticulum of a mutant erythropoietin receptor. Proc. Natl. Acad. Sci. USA. 92:190- 194. 9. , and A.

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Animal Cell Technology: From Vaccines to Genetic Medicine by C. Weissmann (auth.), Manuel J. T. Carrondo, Bryan Griffiths, José L. P. Moreira (eds.)

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