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By Matthias Reumann

ISBN-10: 3866441223

ISBN-13: 9783866441224

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Extra resources for Computer Assisted Optimisation of Non-Pharmacological Treatment of Congestive Heart Failure and Supraventricular Arrhyth

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7) Given jIon = 0, an electrochemical equilibrium state is reached. In this state, no diffusion and no overall ion flux passes through the membrane resulting in a resting potential. 8) EIon is called the equilibrium or Nernst voltage across a membrane for a specific ion of type [Ion] provided the membrane is only permeable for just one single ion type. 1 shows the Nernst voltages for K + , N a+ , Ca2+ and Cl− ions. 1. Typical ion concentration and their associated Nernst voltages of sceletal muscle [266].

Paroxysmal AF Recurrent paroxysmal AF describes episodes of AF lasting from a few seconds up to a few days. Most episodes are self-terminating and convert back into sinus rhythm within seven days. AF events may appear once a year or more frequently. Persistant AF Persistant AF does not spontaneously convert back into sinus rhythm. It lasts longer than seven days by definition. The first occurance of AF may be persistant or episodes of paroxysmal AF may have preceeded persistant AF. Cardioversion (either pharmacological or electrical) is successful treatment in persistant AF.

QRS duration may not be an adequate indicator for dyssynchronous contraction. Over a third of patients with QRS complex length of over 120 ms do not show ventricular dyssynchrony while significant dyssynchrony can be found in about 30 % of patients with narrow QRS complex. Thus, left ventricular dyssynchrony can be rather defined by the electromechanical delay between septum and lateral wall (septal-to-lateral delay). In extensive dyssynchrony, this delay can be over 60 ms [22]. Asynchronous contraction as provoked by electromechanical delays results in a decreased ejection fraction and cardiac output.

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Computer Assisted Optimisation of Non-Pharmacological Treatment of Congestive Heart Failure and Supraventricular Arrhyth by Matthias Reumann

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